I want to add a lots of groups and buttons, can I do this at design time and/or without writing a lot of code?

Certainly. You can add groups and buttons in each group without writing a single line of code. This can be done through the Group and Button property pages. For displaying property pages in VB IDE, right click on the control and select the "Properties" from the context menu that appears. The groups and buttons as well as their properties that you add at design time will be stored in the corresponding frm file (also exe file) and will automatically get loaded at runtime. With this mechanism, you can minimize the code you need to write for providing a professional navigation interface in your application.